According to the information released by the company, 85% of bets placed were in favour of Irish underdog McGregor, while the total stakes were £1m higher for Mayweather.
The average bet piled on by Conor McGregor supporters was £20 while the smart money was placed on Mayweather with an average bet six times higher at £120.
The record yielded an increase of 530% in total stakes and 375% in total number of bets over the previous record betting fight between Mayweather and Manny Pacquiao in 2015.
Keith O’Loughlin, Executive Vice President OpenBet said: "OpenBet proved again that the platform we offer to operators can scale to cover very significant spikes of business. The resilience and scalability of OpenBet allows us to smash previous records with confidence and we continuously offer our customers a great experience 24/7 when it matters most.”
"OpenBet, our customers, punters, Mayweather and McGregor all came out winners on one of the biggest fights in history – that’s pretty unique!” concluded O’Loughlin.